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However, a form known as vitamin E acetate has been found to exist in both nicotine and non-nicotine e-cigarettes, and is associated with lung injury related to e-cigarette or vape product use (EVALI), which may be permanent

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COPD is a heterogeneous condition, with between-individual variation in the nature and severity of airway inflammation [42] and the inflammatory cell profile also varies in large and small airways and with severity of COPD, hence careful appraisal is needed [43]

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